Precision Nutrition for Cardiovascular Diseases Prevention

<b><i>Background:</i></b> Cardiovascular diseases (CVDs) are the leading cause of death globally, making their prevention a major challenge for modern society. For decades, treatments aimed at reducing CVD risk factors through nutritional recommendations and medications have had variable success. One main reasons behind this is interindividual variability in response to drugs interventions. The development genomics has allowed discovery genetic variants influencing drug food response, more personalized form precision medicine nutrition. latter founded on principle that one diet does not fit all need stratify individuals into subgroups based nutrients. Despite showing great promise pushing forward field nutrition, health professionals very little knowledge even though general population interest guidance. <b><i>Summary:</i></b> This review provide an overview key sources observed some limitations, testing mature predictive tool should be forefront tailored nutrition prevention. Although epigenome-diet relationship shows promise, it still too early its allow clinical deployment. Metabolomics potential enhance by complementing traditional self-reported dietary intake instruments as well promising metabotyping method. Microbiome phenotyping, despite complexity, provides wealth information status host Finally, current applications discussed outline required steps successful implementation practice presented. <b><i>Key Messages:</i></b> Precision cornerstone approach offering targeted